Periodontal Health of Pre-Dialysis Chronic Kidney Disease Patients in a Northeast Peninsular Malaysia Tertiary Hospital

Hanim Afzan Ibrahim; Nur Karyatee Kassim; Fatimah Zahra Jamsari; Siti Lailatul Akmar Zainuddin; Muhammad Hafiz Hanafi; Azreen Syazril Adnan

doi:10.21315/mjms2020.27.1.11

Periodontal Health of Pre-Dialysis Chronic Kidney Disease Patients in a Northeast Peninsular Malaysia Tertiary Hospital

Malays J Med Sci. 2020 Feb;27(1):106-114. doi: 10.21315/mjms2020.27.1.11. Epub 2020 Feb 27.

Authors

Hanim Afzan Ibrahim^{1

2}, Nur Karyatee Kassim^{1

2}, Fatimah Zahra Jamsari¹, Siti Lailatul Akmar Zainuddin¹, Muhammad Hafiz Hanafi³, Azreen Syazril Adnan^{4

5}

Affiliations

¹ School of Dental Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
² Chemical Pathology Department, Hospital Universiti Sains Malaysia, Kelantan, Malaysia.
³ School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
⁴ Chronic Kidney Disease Resource Center, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
⁵ Management Science University (MSU) Medical Centre, Shah Alam, Selangor.

Abstract

Introduction: Chronic kidney disease (CKD) is associated with periodontal disease due to its hyperinflammatory state. Limited studies have explored the prevalence of periodontal disease among CKD patients in Malaysia.

Objective: To assess the periodontal status of pre-dialysis CKD patients in Hospital Universiti Sains Malaysia.

Methods: A total of 46 pre-dialysis CKD patients who attended the nephrology clinic at Hospital Universiti Sains Malaysia were enrolled in this study. Periodontal examination was performed using the periodontal probing depth (PPD), clinical attachment loss (CAL) and plaque index.

Results: The majority of the CKD patients were Malay (95.7%) and 80.4% were males. The mean age of the patients was 58.5 years. Using PPD measurement, 37 (74.0%) of the patients had mild periodontitis, 9 (20.0%) had moderate periodontitis and 3 (6.0%) had no periodontitis. Based on CAL measurement, 12 (26%) patients had mild periodontitis, 29 (63.0%) had moderate periodontitis and 5 (11%) had severe periodontitis. The mean (standard deviation [SD]) value of mild and moderate-to-severe periodontitis by PPD measurement were 4.26 (0.26) and 5.24 (0.36), respectively. The mean of mild and moderate-to-severe periodontitis by CAL measurement were 2.66 (0.62) and 4.98 (0.73), respectively. There was no correlation between the periodontal parameters and estimated glomerular filtration rate (PPD: r = -0.160, P = 0.914; CAL: r = -0.135, P = 0.372; plaque index: r = 0.005, P = 0.974).

Conclusion: This study revealed a greater prevalence and severity of chronic periodontitis among CKD patients. Thus, the periodontal health of CKD patients' needs to be screened and monitored.

Keywords: chronic kidney disease; chronic periodontitis; periodontal health; pre-dialysis.