[Assessment of Prognosis after Surgical Treatment for Colorectal Liver Metastasis Using a Nomogram]

Gan To Kagaku Ryoho. 2019 Dec;46(13):1996-1998.
[Article in Japanese]

Abstract

A nomogram is a statistical tool that can provide the specific outcomes of individual patients. In this study, we used a nomogram developed by Beppu et al to evaluate the prognoses of 38 patients who underwent hepaticresec tion at our hospital. This nomogram predicts disease-free survival(DFS)after hepatic resection for colorectal liver metastasis based on 6 clinical and oncological factors. Using this nomogram, we divided the 38 patients into 3 groups: Group N, actual DFS was almost similar to the estimated median DFS(EMDFS)provided by the nomogram; Group A, DFS was longer than EMDFS; and Group B, DFS was shorter than EMDFS. Then, we compared and analyzed clinical and oncological factors between Groups A and B. Group B patients tended to have single metastasis and non-normal levels of CA19-9. Besides, Group B patients had DFS shorter than approximately 2 years. These results suggest that if CA19-9 levels are not normalized after hepaticresec tion for single metastasis, we should consider careful observation and adjuvant chemotherapy for potential micrometastasis.

MeSH terms

  • Colorectal Neoplasms*
  • Disease-Free Survival
  • Hepatectomy
  • Humans
  • Liver Neoplasms* / surgery
  • Nomograms
  • Prognosis
  • Retrospective Studies