[Obstetrics complications of systemic lupus erythematosus and antiphospholipid syndrome: A multidisciplinary management]

Abstract

The main autoimmune diseases responsible for obstetric complications are systemic lupus erythematosus and antiphospholipid syndrome. They are particularly associated with an increased risk of miscarriage, stillbirth, intrauterine growth restriction, prematurity and pre-eclampsia. Therapeutics to prevent its complications are mainly low dose aspirin and low molecular weight heparins. However, the introduction of these therapies will have to consider the benefit/risk ratio to manage pregnancy and especially delivery. Consistency of care provided by autoimmunity specialists and gynaecologist-obstetricians is extremely important and must be promoted through regular exchanges, fuelled by a mutual culture, through multidisciplinary consultation meetings.

Keywords: APS; Aspirin; Aspirine; Harmful effects; Héparine de bas poids moléculaire; Iatrogénie; Low molecular weight heparin; Lupus érythémateux systémique; Multidisciplinary meeting; Réunion de concertation pluridisciplinaire; SAPL; Systemic lupus erythematosus.