Intra-cavitary pulmonary cryptococcoma in poorly controlled diabetes mellitus

Najibu Kalyango; Richard Kwizera; Joseph B Baluku; Felix Bongomin

doi:10.1016/j.mmcr.2020.02.005

Intra-cavitary pulmonary cryptococcoma in poorly controlled diabetes mellitus

Med Mycol Case Rep. 2020 Feb 24:28:1-3. doi: 10.1016/j.mmcr.2020.02.005. eCollection 2020 Jun.

Authors

Najibu Kalyango¹, Richard Kwizera², Joseph B Baluku³, Felix Bongomin^{1

4}

Affiliations

¹ Department of Medicine, College of Health Sciences, Makerere University, Kampala, P.o.Box, 7072, Uganda.
² Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, P.o.Box, 7072, Uganda.
³ Department of Pulmonology, Mulago National Referral Hospital, Kampala, P.o.Box, 7051, Uganda.
⁴ Department of Microbiology and Immunology, Faculty of Medicine, Gulu University, Gulu, P.o.Box 166, Uganda.

Abstract

A 59-year-old HIV-negative Ugandan man presented with a long-standing history of respiratory symptoms and was found to have an intra-cavitary pulmonary cryptococoma by chest imaging and sputum culture. The serum cryptococcal antigen was negative. The sputum Xpert® MTB RIF Ultra assay was negative. He was previously treated for cavitary pulmonary tuberculosis. The patient had poorly controlled diabetes (HbA1c, 9.3%). The patient was successfully treated with oral fluconazole.

Keywords: Aspergillus IgG; Cryptococcal antigen test; Diabetes; Pulmonary cryptococcoma; Tuberculosis.

Publication types

Case Reports

Grants and funding

WT_/Wellcome Trust/United Kingdom