Fast diffraction-enhanced imaging using continuous sample rotation and analyzer crystal scanning

J Synchrotron Radiat. 2020 Mar 1;27(Pt 2):468-471. doi: 10.1107/S1600577519016795. Epub 2020 Jan 28.

Abstract

Diffraction-enhanced imaging (DEI) has high sensitivity and a wide dynamic range of density and thus can be used for fine imaging of biological and organic samples that include large differences in density. A fast DEI method composed of continuous fast sample rotations and slow analyzer crystal scanning was developed to shorten the measurement period. Fine sectional images of a biological sample were successfully obtained within a half measurement period of the conventional step-scanning method while keeping the same exposure time. In addition, a fine three-dimensional image of a rat tail was obtained with a 375 s measurement period.

Keywords: continuous rotation; density resolution; diffraction-enhanced imaging.

MeSH terms

  • Animals
  • Imaging, Three-Dimensional
  • Radiographic Image Enhancement
  • Rats
  • Reproducibility of Results
  • Rotation
  • Sensitivity and Specificity
  • Tail / diagnostic imaging*
  • X-Ray Diffraction / methods*