Presence and Concentrations of Select Bacterial Vaginosis-Associated Bacteria Are Associated With Increased Risk of Pelvic Inflammatory Disease

Sex Transm Dis. 2020 May;47(5):344-346. doi: 10.1097/OLQ.0000000000001164.

Abstract

In a vaginal 16S ribosomal RNA gene quantitative PCR study of 17 pelvic inflammatory disease (PID) cases and 17 controls who tested positive for Chlamydia trachomatis, women who additionally tested positive for Atopobium vaginae, Sneathia spp., Megasphaera spp., Eggerthella-like bacterium or Prevotella amnii were more likely to develop PID.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Actinobacteria
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Bacteria / drug effects*
  • Bacteria / isolation & purification
  • Case-Control Studies
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / genetics
  • Female
  • Humans
  • Pelvic Inflammatory Disease / epidemiology*
  • Polymerase Chain Reaction / methods*
  • Prevotella
  • RNA, Ribosomal, 16S / genetics
  • Vagina / microbiology*
  • Vaginosis, Bacterial / complications
  • Vaginosis, Bacterial / epidemiology*

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S

Supplementary concepts

  • Atopobium vaginae
  • Prevotella amnii