Retinoic acid-loading of the major birch pollen allergen Bet v 1 may improve specific allergen immunotherapy: In silico, in vitro and in vivo data in BALB/c mice

Affiliations

• ¹ The interuniversity Messerli Research Institute of the University of Veterinary Medicine, Medical University of Vienna and University of Vienna, Vienna, Austria.
• ² Laboratory Medicine and Immunology Department, Faculty of Medicine, Menoufia University, Shebin El-Kom, Egypt.
• ³ Department of Biosciences, University of Salzburg, Salzburg, Austria.
• ⁴ Protein Bioinformatics Research Group, Department of Biosciences, University of Salzburg, Salzburg, Austria.
• ⁵ Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
• ⁶ Centre for Plant Biotechnology and Genomics, CBGP (UPM-INIA) and Department of Biotechnology-Plant Biology, Universidad Politécnica de Madrid, Madrid, Spain.
• ⁷ Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University Vienna, Vienna, Austria.
• ⁸ Biomedical International R+D GmbH, Vienna, Austria.