Recurrent Uterine Smooth-Muscle Tumors of Uncertain Malignant Potential (STUMP): State of The Art

Anticancer Res. 2020 Mar;40(3):1229-1238. doi: 10.21873/anticanres.14064.

Abstract

The term 'uterine STUMP' (smooth-muscle tumors of uncertain malignant potential) is currently used to define a heterogeneous group of uterine tumors distinct from leiomyomas and leiomyosarcomas. This rare entity is often characterized by a slow growth and protracted patient survival when compared to leiomyosarcomas but few data are available about its clinical management and outcome. In this review, we summarize the current state of knowledge about uterine STUMP, with a particular focus on cases of recurrence.

Keywords: STUMP; Smooth-muscle tumors of uncertain malignant potential; recurrence; review; uterine malignancies; uterine smooth-muscle neoplasms.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Neoplasm Recurrence, Local
  • Smooth Muscle Tumor / pathology*