Gut Microbes Controlling Blood Sugar: No Fire Required!

Martin Jastroch; Siegfried Ussar; Susanne Keipert

doi:10.1016/j.cmet.2020.02.007

Gut Microbes Controlling Blood Sugar: No Fire Required!

Cell Metab. 2020 Mar 3;31(3):443-444. doi: 10.1016/j.cmet.2020.02.007.

Authors

Martin Jastroch¹, Siegfried Ussar², Susanne Keipert³

Affiliations

¹ Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 106 91 Stockholm, Sweden. Electronic address: martin.jastroch@su.se.
² RG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Department of Medicine, Technische Universität München, Munich, Germany.
³ Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 106 91 Stockholm, Sweden.

PMID: 32130877
DOI: 10.1016/j.cmet.2020.02.007

Abstract

The gut microbiota plays an important role for the absorption of nutrients and the maintenance of metabolism, potentially impacting the development of human metabolic disorders such as obesity and type 2 diabetes. In this issue of Cell Metabolism, Krisko et al. (2020) demonstrate that the gut microbiota regulates glucose homeostasis solely via hepatic gluconeogenesis and not via thermogenic adipose tissue as suggested previously.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Blood Glucose
Diabetes Mellitus, Type 2*
Gastrointestinal Microbiome*
Homeostasis
Humans
Mice
Microbiota*
Thermogenesis

Substances

Blood Glucose