Consolidation with carfilzomib, lenalidomide, and dexamethasone (KRd) following ASCT results in high rates of minimal residual disease negativity and improves bone metabolism, in the absence of bisphosphonates, among newly diagnosed patients with multiple myeloma

Blood Cancer J. 2020 Mar 2;10(3):25. doi: 10.1038/s41408-020-0297-2.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols
  • Bone and Bones / drug effects*
  • Bone and Bones / metabolism
  • Dexamethasone / pharmacology
  • Dexamethasone / therapeutic use*
  • Diphosphonates / pharmacology
  • Diphosphonates / therapeutic use*
  • Female
  • Humans
  • Lenalidomide / pharmacology
  • Lenalidomide / therapeutic use*
  • Male
  • Middle Aged
  • Multiple Myeloma / drug therapy*
  • Neoplasm, Residual / drug therapy*
  • Oligopeptides / pharmacology
  • Oligopeptides / therapeutic use*
  • Prospective Studies

Substances

  • Diphosphonates
  • Oligopeptides
  • carfilzomib
  • Dexamethasone
  • Lenalidomide