Oral transmucosal fentanyl is a medication used in the management and treatment of breakthrough pain. It is in the class of short-acting synthetic opioids. This activity outlines the indications, action, contraindications for oral transmucosal fentanyl as a valuable agent in the treatment and management of breakthrough pain. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of the healthcare team in the management of patients with breakthrough pain.
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