Fosinopril belongs to the class of angiotensin-converting enzyme (ACE) inhibitors used in cardiovascular conditions for nearly 3 decades. Fosinopril has received approval from the United States Food and Drug Administration (FDA) for the treatment of hypertension and heart failure. Being a competitive inhibitor of ACE, fosinopril prevents the conversion of angiotensin I to angiotensin II—a powerful vasoconstrictor. Other ACE inhibitors approved in the United States include captopril, enalapril, lisinopril, benazepril, quinapril, ramipril, moexipril, fosinopril, and trandolapril.
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