The dead space after extirpation of rectum. Current management and searching for new materials for filling

Physiol Res. 2019 Dec 30;68(Suppl 4):S509-S515. doi: 10.33549/physiolres.934390.

Abstract

Pelvic surgeries such as extirpation of the rectum or pelvic exenteration lead to a creation of a dead space, which can be cause of complication, such as bowel obstruction, perineal hernia, abscess or hematoma. A growing incidence of complication is expected in connection with the increasing use of laparoscopic and robotic approaches or ELAPE method. Since the bone structures do not allow compression, the only way to deal with the dead space is to fill it in. Present methods provide the filling with omental or myofascial flaps. The length and the mobility of the omental flap can be the limitation. Myofascial flaps are technically more demanding and bring the complications of a donor place. Synthetic or biological meshes do not deal with dead space problematic. Modern technologies using nanomaterials offer the possibility to produce a material with specific properties for example shape, inner structure, surface, or time of degradation. The modified material could also satisfy the requirements for filling the dead space after surgeries.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials
  • Humans
  • Pelvis / surgery*
  • Postoperative Complications / prevention & control*
  • Rectum / surgery*

Substances

  • Biocompatible Materials