This article investigates a fuzzy adaptive two-bit-triggered control for uncertain nonlinear systems with actuator failures and dead-zone constraint. Actuator failures and dead-zone constraint exist frequently in practical systems, which will affect the system performance greatly. Based on the improved fuzzy-logic systems (FLSs), a fuzzy adaptive compensation control is established to address these issues. The approximation error is introduced to the control design as a time-varying function. In addition, for the limited transmission resources of the practical system, a two-bit-triggered control mechanism is proposed to further save system transmission resources. It is proved that the proposed method can guarantee the system tracking performance and all the signals are bounded. Its effectiveness is verified by the simulation examples.