Candida auris: A Decade of Understanding of an Enigmatic Pathogenic Yeast

Ryan Kean; Jason Brown; Dolunay Gulmez; Alicia Ware; Gordon Ramage

doi:10.3390/jof6010030

Candida auris: A Decade of Understanding of an Enigmatic Pathogenic Yeast

J Fungi (Basel). 2020 Feb 26;6(1):30. doi: 10.3390/jof6010030.

Authors

Ryan Kean¹, Jason Brown², Dolunay Gulmez^{2

3}, Alicia Ware¹, Gordon Ramage²

Affiliations

¹ Department of Biological and Biomedical Sciences, School of Health and Life Sciences, Glasgow Caledonian University, Glasgow G4 0BA, UK.
² School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences, Glasgow G2 3JZ, UK.
³ Medical Microbiology Department, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.

Abstract

Candida auris is an enigmatic yeast that continues to stimulate interest within the mycology community due its rapid and simultaneous emergence of distinct clades. In the last decade, almost 400 manuscripts have contributed to our understanding of this pathogenic yeast. With dynamic epidemiology, elevated resistance levels and an indication of conserved and unique pathogenic traits, it is unsurprising that it continues to cause clinical concern. This mini-review aims to summarise some of the key attributes of his remarkable pathogenic yeast.

Keywords: Candida auris; biofilms; in vivo models; pathogenicity.

Publication types

Review