Stopping sperm in their tracks

Luke L McGoldrick; Jean-Ju Chung

doi:10.7554/eLife.55396

Stopping sperm in their tracks

Elife. 2020 Feb 27:9:e55396. doi: 10.7554/eLife.55396.

Authors

Luke L McGoldrick¹, Jean-Ju Chung^{1

2}

Affiliations

¹ Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, United States.
² Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, United States.

Abstract

An automated high-throughput platform can screen for molecules that change the motility of sperm cells and their ability to fertilize.

Keywords: acrosome reaction; contraception; developmental biology; high-throughput screening; human; human biology; infertility; medicine; motility; sperm.

Publication types

Comment

MeSH terms

Contraceptive Agents* / pharmacology
Fertilization
Humans
Male
Sperm Motility*
Spermatozoa

Substances

Contraceptive Agents

Grants and funding

R01 HD096745/HD/NICHD NIH HHS/United States