Prolonged elevation of plasma HMGB1 is associated with cognitive impairment in intensive care unit survivors

Affiliations

• ¹ Department of Physiology and Pharmacology, Karolinska Institute, 171 77, Stockholm, Sweden.
• ² Laboratory of Immunobiology, Center for Bioelectronic Medicine, Department of Medicine, Solna, Karolinska Institute, Bioclinicum, Karolinska University Hospital, 171 76, Stockholm, Sweden.
• ³ Stress Research Institute, Stockholm University, 106 91, Stockholm, Sweden.
• ⁴ Division of Psychology, Department of Clinical Neuroscience, Karolinska Institute, 171 77, Stockholm, Sweden.
• ⁵ Department of Women's and Children's Health, Karolinska Institute, 171 77, Stockholm, Sweden.
• ⁶ Laboratory of Immunobiology, Center for Bioelectronic Medicine, Department of Medicine, Solna, Karolinska Institute, Bioclinicum, Karolinska University Hospital, 171 76, Stockholm, Sweden. peder.olofsson@ki.se.
• ⁷ Laboratory of Biomedical Sciences, The Feinstein Institute for Medical Research, Manhasset, NY, USA. peder.olofsson@ki.se.