Ir(iii)-Catalyzed direct C-H functionalization of N-phenylacetamide with α-diazo quinones: a novel strategy for producing 2-hydroxy-2'-amino-1,2'-biaryl scaffolds

Abstract

α-Diazo quinones were applied in an Ir(iii)-catalyzed direct C-H functionalization assisted by N-phenylacetamide for the construction of highly functionalized 2-hydroxy-2'-amino-1,1'-biaryl scaffolds in good to excellent yields. This strategy features operational simplicity, atom- and step-economy and high efficiency.