Measles outbreak in Dubrovnik-Neretva County, Croatia, May to June 2018

Euro Surveill. 2020 Feb;25(7):1900434. doi: 10.2807/1560-7917.ES.2020.25.7.1900434.

Abstract

In May 2018, measles was introduced in the Dubrovnik region by an adult who recently travelled to Kosovo*. Control measures and an outbreak investigation were implemented: 15 epidemiologically-linked cases met the outbreak case definition of a visitor/resident of Dubrovnik-Neretva County with laboratory-confirmed measles and symptom onset beginning on May 19. New cases were identified through hospitals and primary care physicians. Throat swabs, urine and/or serum samples were collected from outbreak cases. RT-PCR detection of viral RNA and IgM/IgG was used to confirm infection. The median age of cases was 33 years, with one 8 month-old infant. Vaccination status was unknown for 9 cases, three were unvaccinated, one case had history of one dose and two cases reported receiving two doses of measles-containing vaccine. There were 11 hospitalisations and one person developed pneumonia. Control teams undertook an extensive search of contacts and implemented a range of control measures. Despite the outbreak occurring at the beginning of the summer tourism season, it was contained and did not spread to neighbouring regions. With continuing measles transmission in Europe, even small outbreaks create a burden on the health system in countries which have eliminated measles, and illustrate the importance of maintaining high immunisation coverage.

Keywords: Croatia; airborne infections; communicable diseases; disease outbreak; measles; vaccination; viral infections.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Viral / blood*
  • Child
  • Child, Preschool
  • Contact Tracing
  • Croatia / epidemiology
  • Disease Outbreaks*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Infant
  • Male
  • Measles / epidemiology*
  • Measles / immunology
  • Measles Vaccine / administration & dosage*
  • Middle Aged
  • Morbillivirus / genetics
  • Morbillivirus / isolation & purification*
  • RNA, Viral
  • Reverse Transcriptase Polymerase Chain Reaction
  • Vaccination*

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M
  • Measles Vaccine
  • RNA, Viral