MEIOSIN: A New Watchman of Meiotic Initiation in Mammalian Germ Cells

Jon M Oatley; Michael D Griswold

doi:10.1016/j.devcel.2020.02.002

MEIOSIN: A New Watchman of Meiotic Initiation in Mammalian Germ Cells

Dev Cell. 2020 Feb 24;52(4):397-398. doi: 10.1016/j.devcel.2020.02.002.

Authors

Jon M Oatley¹, Michael D Griswold²

Affiliations

¹ Center for Reproductive Biology, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA. Electronic address: joatley@wsu.edu.
² Center for Reproductive Biology, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.

Abstract

The capacity to undergo meiosis defines vertebrate germ cells, yet mechanisms driving initiation of this specialized process are largely undefined. In this issue of Developmental Cell,Ishiguro et al. (2020) identified the transcription factor MEIOSIN as a gatekeeper of meiotic initiation in both male and female germ cells.

Publication types

Comment

MeSH terms

Animals
Female
Gene Expression Regulation
Germ Cells*
Male
Meiosis*
Mitosis
Transcription Factors

Substances

Transcription Factors

Abstract

Publication types

MeSH terms

Substances

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