Previous studies in the long-term experiments at Pendleton, OR (USA), were focused on organic matter cycling, but the consequences of land management for nutrient status over time have received little attention. Soil and wheat (Triticum aestivum L.) tissue samples were analyzed to determine the macronutrient dynamics associated with residue management methods and fertilizer rate under a dryland winter wheat-fallow rotation. The treatments included: no burn residue incorporation with farmyard manure (FYM) or pea vines, no burn or spring burn with application of N fertilizer (0, 45, and 90 kg ha-1), and fall burn wheat residue incorporation. The results revealed no differences on the effect of residue burning on macronutrient concentration over time. After receiving the same treatments for 84 years, the concentrations of soil organic C, total N and S, and extractable Mg, K, P in the 0-10 cm depth significantly increased in FYM plots compared to the rest of the plots. The N fertilization rate of 90 kg ha-1 reduced the accumulations of P, K, and Ca in grain compared to the 0 and 45 kg N ha-1 applications. The results indicate that residue incorporation with FYM can play vital role in reducing the macronutrient decline over time.