Effect of Traditional Chinese Medicine on Long-Term Outcomes of Snakebite in Taiwan

Toxins (Basel). 2020 Feb 20;12(2):132. doi: 10.3390/toxins12020132.

Abstract

Herein, we review the characteristics of the six predominant venomous snakes in Taiwan and the effects of traditional Chinese medicine on the long-term outcomes of snakebite venom. We electronically searched databases, including PubMed, ClinicalKey, China National Knowledge Infrastructure, National Digital Library of Theses and Dissertations in Taiwan, and Airiti Library, from their inception to November 2019 by using the following Medical Subject Headings' keywords: snakebite, long-term, chronic, Chinese medicine, CAM, herb, and Taiwan. The most common long-term effects of snakebite envenomation include "migraine-like syndrome", brain injuries caused by hypoxia or intracranial hemorrhage, and chronic kidney disease. In addition, hypopituitarism is also worth mentioning. Traditional Chinese medicine can potentially be used in a complementary or alternative treatment for these effects, but additional studies are needed.

Keywords: long-term effects; snakebites; traditional Chinese medicine; venom.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain Diseases / drug therapy*
  • Brain Diseases / etiology
  • Cerebral Infarction / drug therapy
  • Cerebral Infarction / etiology
  • Drugs, Chinese Herbal / administration & dosage
  • Drugs, Chinese Herbal / therapeutic use*
  • Humans
  • Hypopituitarism / drug therapy*
  • Hypopituitarism / etiology
  • Intracranial Hemorrhages / drug therapy
  • Intracranial Hemorrhages / etiology
  • Medicine, Chinese Traditional*
  • Migraine Disorders / drug therapy
  • Migraine Disorders / etiology
  • Renal Insufficiency, Chronic / drug therapy*
  • Renal Insufficiency, Chronic / etiology
  • Snake Bites / complications*
  • Taiwan

Substances

  • Drugs, Chinese Herbal