The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]
Review
7th edition. Cham (CH): Springer; 2019.
Editors
Enric Carreras
1
,
Carlo Dufour
2
,
Mohamad Mohty
3
,
Nicolaus Kröger
4
Affiliations
1
Spanish Bone Marrow Donor Registry, Josep Carreras Foundation and Leukemia Research Institute, Catalunya, Barcelona, Spain
2
Hematology Unit, IRCCS Giannina Gaslini, Geneva, Switzerland
3
Department of Hematology, Pierre and Marie Curie University, Paris, France
4
Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppend, Hamburg, Germany
PMID:
32091673
Bookshelf ID:
NBK553942
DOI:
10.1007/978-3-030-02278-5
No abstract available
Copyright 2019, The Editor(s) (if applicable) and The Author(s).
Sections
Preface
Acknowledgment
Abbreviations
Contributors
About the Editors
I. Introduction Topic leaders: Mohamad Mohty and Jane Apperley
1. HSCT: Historical Perspective
2. The EBMT: History, Present, and Future
3. The Role of Unrelated Donor Registries in HSCT
4. The HSCT Unit
5. JACIE Accreditation of HSCT Programs
6. Statistical Methods in HSCT and Cellular Therapies
II. Biological Aspects Topic leaders: Chiara Bonini and Jürgen Kuball
7. Biological Properties of HSC: Scientific Basis for HSCT
8. Biological Properties of Cells Other Than HSCs
9. Histocompatibility
10. Clinical and Biological Concepts for Mastering Immune Reconstitution After HSCT: Toward Practical Guidelines and Greater Harmonization
III. Methodology and Clinical Aspects Topic leaders: Arnon Nagler and Nicolaus Kröger
11. Evaluation and Counseling of Candidates
12. Donor Selection for Adults and Pediatrics
13. Conditioning
14. Bone Marrow Harvesting for HSCT
15. Mobilization and Collection of HSC
16. Collection of HSC in Children
17. Processing, Cryopreserving and Controlling the Quality of HSCs
18. Procurement and Management of Cord Blood
19. Graft Manipulation
20. Documentation of Engraftment and Chimerism After HSCT
21. Short- and Long-Term Controls After HSCT
IV. General Management of the Patient Topic leaders: Carlo Dufour, Silvia Montoto and John Murray
22. Vascular Access
23. Transfusion Support
24. Nutritional Support
25. GVHD Prophylaxis (Immunosuppression)
26. Management ATG (SIRS)
27. Infection Control and Isolation Procedures
28. General Management of the Patient: Specific Aspects of Children
29. Vaccinations
30. Psychological Morbidity and Support
31. Clinically Relevant Drug Interactions in HSCT
32. Role of Nursing in HSCT
33. Ethical Issues in HSCT
34. Quality of Life Assessment After HSCT for Pediatric and Adults
V. HSCT Complications and Management Topic leaders: Jan Styczynski, Enric Carreras and Per Ljungman
35. Neutropenic Fever
36. Bacterial Infections
37. Invasive Fungal Infections
38. Viral Infections
39. Other Life-Threatening Infections
40. Bleeding and Thrombotic Complications
41. Graft Failure
42. Early Complications of Endothelial Origin
43. Acute Graft-Versus-Host Disease
44. Chronic Graft-Versus-Host Disease
45. Post transplant Lymphoproliferative Syndromes
46. Iron Overload
47. Secondary Neoplasia (Other than PTLPS)
VI. Specific Organ Complications Topic leaders: Grzegorz Basak and John Snowden
48. Ocular and Oral Complications
49. Hepatic Complications
50. Gastrointestinal Complications
51. Haemorrhagic Cystitis and Renal Dysfunction
52. Noninfectious Pulmonary Complications
53. Neurological Complications
54. Skin, Hair and Musculoskeletal Complications
55. Cardiovascular Diseases and Metabolic Syndrome
56. Endocrine Disorders, Fertility and Sexual Health
VII. Prevention and Management of Relapse Topic leaders: Peter Bader and Nicolaus Kröger
57. Monitoring Minimal Residual Disease in ALL and AML
58. Prevention and Treatment of Relapse by Drugs
59. Delayed Transfer of Immune Cells or the Art of Donor Lymphocyte Infusion
60. Cellular Therapy with Engineered T Cells, Efficacy and Side Effects
61. Mechanisms of Immune Resistance
62. Regulatory Aspects of ATMP Versus Minimally Manipulated Immune Cells
VIII. Specific Modalities of HSCT and Management Topic leaders: Andrew Gennery, Anna Sureda and Arjan Lankester
63. At-Home HSCT
64. Umbilical Cord Blood Transplantation in Children and Adults
65. Haploidentical HSCT
66. Photopheresis in Adults and Pediatrics
67. Overweight and Obese Patients
68. HSCT in Elderly Patients
IX. Indications and Results Topic leaders: Rafael Duarte and Nicolaus Kröger
69. Acute Myeloid Leukemia in Adults
70. Acute Myeloid Leukemia in Children
71. Acute Lymphoblastic Leukemia in Adults
72. Acute Lymphoblastic Leukemia in Children and Adolescents
73. Myelodysplastic Syndromes
74. Pediatric MDS Including Refractory Cytopenia and Juvenile Myelomonocytic Leukemia
75. Myelodysplastic/Myeloproliferative Neoplasms
76. Myeloproliferative Neoplasms
77. Severe Aplastic Anemia and PNH
78. Fanconi’s Anemia and Other Hereditary Bone Marrow Failure Syndromes
79. Hemoglobinopathies (Sickle Cell Disease and Thalassemia)
80. Multiple Myeloma
81. Systemic Light Chain Amyloidosis
82. POEMS Syndrome and Disease Produced by Other Monoclonal Immunoglobulins
83. Follicular Lymphoma
84. Chronic Lymphocytic Leukemia
85. Diffuse Large B-Cell Lymphoma
86. Mantle Cell Lymphoma
87. Other T- and B-Aggressive Lymphomas and Lymphomas Associated with HIV
88. Classical Hodgkin’s Lymphoma
89. Primary Immunodeficiencies
90. Inborn Errors of Metabolism and Osteopetrosis
91. Autoimmune Disease
92. Solid Tumours
Appendix: EBMT Registry
Publication types
Review