Characterization of electron beam deposited Nb2O5 coatings for biomedical applications

Mihaela Dinu; Laurentiu Braic; Sibu C Padmanabhan; Michael A Morris; Irina Titorencu; Vasile Pruna; Anca Parau; Nadezhda Romanchikova; Leslie F Petrik; Alina Vladescu

doi:10.1016/j.jmbbm.2019.103582

Characterization of electron beam deposited Nb₂O₅ coatings for biomedical applications

J Mech Behav Biomed Mater. 2020 Mar:103:103582. doi: 10.1016/j.jmbbm.2019.103582. Epub 2019 Dec 12.

Authors

Affiliations

¹ National Institute of Research and Development for Optoelectronics INOE 2000, 409 Atomistilor St., Magurele, Romania.
² National Institute of Research and Development for Optoelectronics INOE 2000, 409 Atomistilor St., Magurele, Romania. Electronic address: laurentiu.braic@inoe.ro.
³ University College Cork, Department of Chemistry, College Road, Cork, Ireland; Advanced Materials and BioEngineering Research (AMBER), Trinity College Dublin, College Green, Dublin 2, Ireland.
⁴ Institute of Cellular Biology and Pathology "Nicolae Simionescu" of the Romanian Academy, 8 B.P. Hasdeu, 050568, Bucharest, Romania.
⁵ Institute of Organic Synthesis, 21 Aizkraukles St., LV-1006, Riga, Latvia.
⁶ University of the Western Cape, Department of Chemistry, Robert Sobukwe Road, Bellville, Cape Town, South Africa.
⁷ National Institute of Research and Development for Optoelectronics INOE 2000, 409 Atomistilor St., Magurele, Romania; National Research Tomsk Polytechnic University, 43 Lenin Avenue, 634050, Tomsk, Russia.

PMID: 32090911
DOI: 10.1016/j.jmbbm.2019.103582

Abstract

Niobium oxide coatings deposited on Ti₆Al₄V substrates by electron beam deposition and annealed in air at 600 °C and 800 °C were evaluated for their suitability towards dental, maxillofacial or orthopaedic implant applications. A detailed physico-chemical properties investigation was carried out in order to determine their elemental and phase composition, surface morphology and roughness, mechanical properties, wettability, and corrosion resistance in simulated body fluid solution (pH = 7.4) at room temperature. The biocompatibility of the bare Ti₆Al₄V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. The coatings annealed at 800 °C exhibit more phase pure nanocrystalline Nb₂O₅ surfaces with enhanced wettability, reduced porosity and enhanced corrosion resistance properties making them good candidate for dental, maxillofacial or orthopaedic implant applications.

Keywords: Adhesion; Annealed niobium oxide coatings; Biocompatibility; Corrosion resistance; Electron beam deposition; Hardness; Reduced elastic modulus; Tribological properties.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Coated Materials, Biocompatible*
Corrosion
Electrons
Humans
Materials Testing
Niobium*
Surface Properties
Titanium

Substances

Coated Materials, Biocompatible
Niobium
Titanium