Health-related quality of life in patients with heart failure eligible for treatment with sacubitril-valsartan

Nurs Open. 2019 Nov 19;7(2):556-562. doi: 10.1002/nop2.420. eCollection 2020 Mar.

Abstract

Aim: To describe and compare self-reported health-related quality of life between younger and older patients with severe heart failure eligible for treatment with sacubitril-valsartan and to explore the association between health-related quality of life and age, NYHA classification, systolic blood pressure and NT-proBNP level.

Design: Cross-sectional study.

Methods: A total of 59 patients, eligible for treatment with sacubitril-valsartan were consecutively included and divided into a younger (≤75 years) and older group (>75 years). Health-related quality of life was assessed using the Kansas City Cardiomyopathy Questionnaire and the EuroQol 5-dimensions. Data were collected between June 2016 and January 2018. The STROBE checklist was used.

Results: There were no differences in overall health-related quality of life between the age groups. The older patients reported lower scores in two domains measured with the Kansas City Cardiomyopathy Questionnaire, namely self-efficacy (67.0 SD 22.1 vs. 78.8 SD 19.7) and physical limitation (75.6 SD 19.0 vs. 86.3 SD 14.4). Higher NYHA class was independently associated with lower Kansas City Cardiomyopathy Questionnaire Overall Summary Score.

Keywords: health‐related quality of life; heart failure; self‐care; self‐efficacy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminobutyrates
  • Biphenyl Compounds
  • Cross-Sectional Studies
  • Drug Combinations
  • Heart Failure* / drug therapy
  • Humans
  • Quality of Life*
  • Valsartan

Substances

  • Aminobutyrates
  • Biphenyl Compounds
  • Drug Combinations
  • Valsartan
  • sacubitril and valsartan sodium hydrate drug combination