Complete Response to Immunotherapy Plus Chemotherapy After an Unusual Clinical Response to Afatinib and Stereotactic Radiosurgery in a Patient With Metastatic EGFR-Mutant Non-Small-Cell Lung Cancer

Clin Lung Cancer. 2020 Jul;21(4):e250-e254. doi: 10.1016/j.cllc.2020.01.012. Epub 2020 Jan 27.
No abstract available

Keywords: Checkpoint inhibitors; Lung cancer; Next-generation sequencing; Radiation therapy; Somatic copy number alterations.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Afatinib / therapeutic use*
  • Antineoplastic Agents / therapeutic use*
  • Carcinoma, Non-Small-Cell Lung / secondary
  • Carcinoma, Non-Small-Cell Lung / therapy*
  • Combined Modality Therapy
  • ErbB Receptors / genetics
  • Humans
  • Immunotherapy / methods*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy*
  • Male
  • Mutation*
  • Prognosis

Substances

  • Antineoplastic Agents
  • Afatinib
  • EGFR protein, human
  • ErbB Receptors