Hysteroscopic Treatment of Primary Endometrial Marginal Zone B-cell Lymphoma (MALToma)

F Scrimin; G Magoga; G Di Lorenzo; F Romano; M C De Angelis; A Vitagliano; J Crugno; A Di Spiezio Sardo

Hysteroscopic Treatment of Primary Endometrial Marginal Zone B-cell Lymphoma (MALToma)

Facts Views Vis Obgyn. 2019 Sep;11(3):257-260.

Authors

F Scrimin¹, G Magoga², G Di Lorenzo¹, F Romano¹, M C De Angelis³, A Vitagliano⁴, J Crugno⁵, A Di Spiezio Sardo³

Affiliations

¹ Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.
² Istituto di Ginecologia e Obstetricia, Università Cattolica del Sacro Cuore, Rome, Italy.
³ Department of Public Health, School of Medicine, University of Naples Federico II, Naples, Italy.
⁴ Department of Women and Children's Health, Unit of Gynecology and Obstetrics, University of Padua, Padua, 35128, Italy.
⁵ Obstetrics, Gynecology and Reproductive Sciences Department. University of Miami. Miller School of Medicine. Miami, FL USA.

PMID: 32082533
PMCID: PMC7020950

Abstract

Primary extranodal marginal zone B-cell lymphomas (MALToma) of the endometrium are rare tumors. We report a case of MALToma diagnosed within an endometrial polyp in a patient presenting with postmenopausal vaginal bleeding. The patient underwent a conventional hysteroscopic procedure for intrauterine polyps. There was no suspicion of malignancy during the preoperative investigations or at surgery. Conventional bipolar resection of the polyps was performed. The present case demonstrates that conservative management of endometrial MALToma may be considered as a safe alternative to hysterectomy. Further data on long-term follow up is needed to confirm the safety of this conservative approach.

Keywords: MALT; hysteroscopy; polyp; primary extranodal marginal zone B-cell lymphoma.

Publication types

Case Reports