This study aims to design and implement a very large scale integration (VLSI) chip of the extend InfoMax independent component analysis (ICA) algorithm which can separate the super-Gaussian source signals. In order to substantially reduce the circuit area, the proposed circuit utilizes the time sharing matrix multiplication array (MMA) to realize a series of matrix multiplication operations and employs the coordinate rotation digital computer (CORDIC) algorithm to calculate the hyperbolic functions sinh(θ) and cosh(θ) with the rotation of the hyperbolic coordinate system. Also, the rotation of the linear coordinate system of the CORDIC is adopted for the design of a divider used for obtaining the required function value of tanh(θ) simply by evaluating sinh(θ)/cosh(θ). Implemented in a TSMC 90-nm CMOS technology, the proposed ICA has an operation frequency of 100 MHz with 90.8 K gate counts. Furthermore, the measurement results show the ICA core can be successfully applied to separating mixed medical signals into independent sources.