Where Do We Stand with Closed-Loop Systems and Their Challenges?

Diabetes Technol Ther. 2020 Jul;22(7):485-491. doi: 10.1089/dia.2019.0469. Epub 2020 May 22.

Abstract

Treatments for type 1 diabetes have advanced significantly over recent years. There are now multiple hybrid closed-loop systems commercially available and additional systems are in development. Challenges remain, however. This review outlines the recent advances in closed-loop systems and outlines the remaining challenges, including post-prandial hyperglycemia and exercise-related dysglycemia.

Keywords: Artificial pancreas; Closed-loop; Continuous glucose monitor.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Blood Glucose
  • Blood Glucose Self-Monitoring
  • Diabetes Mellitus, Type 1* / drug therapy
  • Exercise
  • Humans
  • Hyperglycemia
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Insulin Infusion Systems
  • Pancreas, Artificial*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin