Improving the diagnostic accuracy of appendicitis using a multidisciplinary pathway

J Pediatr Surg. 2020 May;55(5):889-892. doi: 10.1016/j.jpedsurg.2020.01.040. Epub 2020 Jan 31.

Abstract

Background/purpose: Improvement opportunities exist in the accuracy and timeliness of the diagnosis of childhood appendicitis. The purpose of our study was to conduct a post-implementation audit of a diagnostic pathway for children with suspected appendicitis presenting to our pediatric emergency department.

Methods: We adopted a diagnostic pathway that utilized a validated risk of appendicitis stratification tool (Alvarado Score) with protocolized use of abdominal ultrasound for moderate risk patients. We conducted a 10% convenience sample audit of pathway patients treated over the subsequent 18-month period. Outcome measures included false negative and positive rates, sensitivity, specificity, and overall pathway accuracy.

Results: One hundred thirty-four pathway patients, of which 22 (16.4%) had appendicitis confirmed pathologically, were evaluated. The risk group distribution of patients was: low risk (29%), moderate risk (60%), and high risk (11%). The negative appendectomy rate was 4.4% (reduced from 14% pre-pathway), and the false negative (missed appendicitis) rate was 3.0%. No patients received CT scans. Pathway sensitivity was 81.8%% (95% CI 59.7% to 94.8%), specificity-92.9%% (95% CI 86.4%-96.9%), and overall accuracy-91.0% (95% CI 84.9%-95.3%).

Conclusion: Implementation of a diagnostic pathway achieved a high level of accuracy and reduced our institutional negative appendectomy rate by 67%. The audit identified additional pathway improvement opportunities.

Levels of evidence: Level IV.

Keywords: Alvarado score; Appendicitis; Diagnostic pathway; Pediatric; Ultrasound.

MeSH terms

  • Adolescent
  • Appendectomy
  • Appendicitis / diagnosis*
  • Appendicitis / diagnostic imaging
  • Appendicitis / surgery
  • Appendix / diagnostic imaging
  • Child
  • Child, Preschool
  • Clinical Audit
  • Confidence Intervals
  • Diagnostic Techniques and Procedures / standards
  • Emergency Service, Hospital
  • Female
  • Humans
  • Male
  • Risk Factors
  • Sensitivity and Specificity
  • Ultrasonography