Anxiety disorders in acute central nervous system infections

Ital J Pediatr. 2020 Feb 17;46(1):23. doi: 10.1186/s13052-020-0788-6.

Abstract

Background: Patients affected by acute central nervous system (ACNS) infectionsmay present different complications, including neuropsychological disorders. Nevertheless, psychopathological impairment has been rarely measured by appropriate and validated tests.

Material and methods: Survivors of childhood ACNS infections admitted to the Bambino Gesù Children's Hospital, Rome, Italy, from June 2013 to June 2015 were re-evaluated at follow-up from June 2016 to June 2017. Both patients and their parents underwent a psychological interview and neuropsychological tests (the Leiter International Performance Scale - revised (Leiter-R), the Child Behaviour Checklist (CBCL), the K-SADS-PL test).

Results: Thirty children were included in the study. The mean score of IQ and fluid reasoning was within the normal range. A percentage of 20% of the children enrolled showed criteria for generalized anxiety disorder.

Conclusion: Our study revealed the importance of follow-up evaluations after ACNS infections, in order to prevent mayor psychological sequelae and to perform treatment or rehabilitation.

Keywords: Acute central nervous system infections; Children; Neuropsychological disorders.

MeSH terms

  • Acute Disease
  • Adolescent
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / epidemiology*
  • Central Nervous System Infections / complications*
  • Central Nervous System Infections / psychology*
  • Child
  • Child, Preschool
  • Cognition
  • Cohort Studies
  • Female
  • Humans
  • Intelligence
  • Italy
  • Male
  • Neuropsychological Tests