Uranium in drinking water: a public health threat

Arch Toxicol. 2020 May;94(5):1551-1560. doi: 10.1007/s00204-020-02676-8. Epub 2020 Feb 17.

Abstract

Uranium (U) has no known essential biological functions. Furthermore, it is well known for its toxicity, radioactivity, and carcinogenic potency. Impacts on human health due to U exposure have been studied extensively by many researchers. Chronic exposure to low-level U isotopes (radionuclides) may be interlinked with cancer etiology and at high exposure levels, also kidney disease. Other important issues covered U and fertilizers, and also U in soils or human tissues as an easily measurable indicator element in a pathophysiological examination. Furthermore, phosphate fertilization is known as the important source of contamination with U in the agricultural land, mainly due to contamination in the phosphate rock applied for fertilizer manufacture. Therefore, long-term usage of U-bearing fertilizers can substantially increase the concentration of U in fertilized soils. It should also be noted that U is an active redox catalyst for the reaction between DNA and H2O2. This review is aimed to highlight a series on various hydro-geochemical aspects in different water sources and focused on the comparison of different U contents in the drinking water sources and presentation of data in relation to health issues.

Keywords: DNA; Groundwater; Health; Indicator element; Soils; Uranium.

Publication types

  • Review

MeSH terms

  • Drinking Water / chemistry*
  • Environmental Exposure / statistics & numerical data*
  • Environmental Monitoring
  • Fertilizers
  • Humans
  • Public Health
  • Uranium / analysis*
  • Water Pollutants, Radioactive / analysis*
  • Water Pollution, Radioactive / statistics & numerical data

Substances

  • Drinking Water
  • Fertilizers
  • Water Pollutants, Radioactive
  • Uranium