Plasticity in olfactory bulb circuits

An Wu; Bin Yu; Takaki Komiyama

doi:10.1016/j.conb.2020.01.007

Plasticity in olfactory bulb circuits

Curr Opin Neurobiol. 2020 Oct:64:17-23. doi: 10.1016/j.conb.2020.01.007. Epub 2020 Feb 13.

Authors

An Wu¹, Bin Yu², Takaki Komiyama³

Affiliations

¹ Neurobiology Section, Center for Neural Circuits and Behavior, University of California San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California San Diego, La Jolla, CA 92093, USA.
² Neurobiology Section, Center for Neural Circuits and Behavior, University of California San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California San Diego, La Jolla, CA 92093, USA; Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA 92093, USA.
³ Neurobiology Section, Center for Neural Circuits and Behavior, University of California San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: tkomiyama@ucsd.edu.

Abstract

Olfaction is crucial for animal survival and human well-being. The olfactory bulb is the obligatory input station for olfactory information. In contrast to the traditional view as a static relay station, recent evidence indicates that the olfactory bulb dynamically processes olfactory information in an experience-dependent and context-dependent manner. Here, we review recent studies on experience-dependent plasticity of the main circuit components within the olfactory bulb of rodents. We argue that the olfactory bulb plasticity allows optimal representations of behaviorally-relevant odors in the continuously changing olfactory environment.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Animals
Odorants
Olfactory Bulb*
Olfactory Pathways*
Smell

Abstract

Publication types

MeSH terms

Grants and funding