Outcomes of exclusive radiation therapy for older women with breast cancer according to age and comorbidity status: An observational retrospective study

Breast J. 2020 May;26(5):976-980. doi: 10.1111/tbj.13764. Epub 2020 Feb 14.

Abstract

The management of older patients with breast cancer, a public health issue, remains a highly topical subject. Among this heterogeneous population, only few studies have focused on outcomes of older women treated with exclusive radiation therapy for localized BC. This retrospective study provides data concerning the efficacy and safety of exclusive RT, as well as the impact of comorbidities according to the Charlson Comorbidity Index on survival in this subset of women not suitable for surgery or who have refused it. This analysis demonstrates that this treatment is well-tolerated; however, the prognosis is strongly impacted by age and comorbidities.

Keywords: breast cancer; comorbidities; older women; radiation therapy.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Breast Neoplasms* / epidemiology
  • Breast Neoplasms* / radiotherapy
  • Comorbidity
  • Female
  • Humans
  • Prognosis
  • Retrospective Studies
  • Treatment Outcome