A meta-analysis of the medium- and long-term effects of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass

BMC Surg. 2020 Feb 12;20(1):30. doi: 10.1186/s12893-020-00695-x.

Abstract

Background: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are two representative bariatric surgeries. This study aimed to compare the effects of the LSG and LRYGB based on high-quality analysis and massive amount of data.

Methods: For this study databases of PubMed, Web of Science, EBSCO, Medline, and Cochrane Library were searched for articles published until January 2019 comparing the outcomes of LSG and LRYGB.

Results: This study included 28 articles. Overall, 9038 patients (4597, LSG group; 4441, LRYGB group) were included. The remission rate of type 2 diabetes mellitus (T2DM) in the LRYGB group was superior to that in the LSG group at the 3-years follow-up. Five-year follow-up results showed that LRYGB had an advantage over LSG for the percentage of excess weight loss and remission of T2DM, hypertension, dyslipidemia, and abnormally low-density lipoprotein.

Conclusions: In terms of the long-term effects of bariatric surgery, the effect of LRYGB was better than of LSG.

Keywords: Effects; Meta-analysis; Roux-en-Y gastric bypass; Sleeve gastrectomy.

Publication types

  • Comparative Study
  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Bariatric Surgery / methods
  • Diabetes Mellitus, Type 2 / epidemiology
  • Gastrectomy / methods*
  • Gastric Bypass / methods*
  • Humans
  • Hypertension / epidemiology
  • Laparoscopy / methods
  • Obesity, Morbid / surgery*
  • Treatment Outcome
  • Weight Loss