Health Properties and Composition of Honeysuckle Berry Lonicera caerulea L. An Update on Recent Studies

Molecules. 2020 Feb 9;25(3):749. doi: 10.3390/molecules25030749.

Abstract

Lonicera caerulea L., also known as haskap or honeysuckle berry, is a fruit commonly planted in eastern Europe, Canada and Asia. The fruit was registered as a traditional food from a third country under European Union regulations only on December 2018. It is resistant to cold, pests, various soil acidities and diseases. However, its attractiveness is associated mostly with its health properties. The fruit shows anticancer, anti-inflammatory, and antioxidant activity-important factors in improving health. These features result from the diverse content of phytochemicals in honeysuckle berries with high concentrations of phytocompounds, mainly hydroxycinnamic acids, hydroxybenzoic acids, flavanols, flavones, isoflavones, flavonols, flavanones and anthocyanins but also iridoids, present in the fruit in exceptional amounts. The content and health properties of the fruit were identified to be dependent on cultivar, genotype and the place of harvesting. Great potential benefits of this nutritious food are its ability to minimize the negative effects of UV radiation, diabetes mellitus and neurodegenerative diseases, and to exert hepato- and cardioprotective activity.

Keywords: Lonicera caerulea; anthocyanins; biological activity; iridoids; polyphenols.

Publication types

  • Review

MeSH terms

  • Anthocyanins / chemistry
  • Anthocyanins / isolation & purification*
  • Anthocyanins / pharmacology
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / isolation & purification
  • Antineoplastic Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Asia
  • Canada
  • Cardiotonic Agents / chemistry
  • Cardiotonic Agents / isolation & purification
  • Cardiotonic Agents / pharmacology
  • Coumaric Acids / chemistry
  • Coumaric Acids / isolation & purification*
  • Coumaric Acids / pharmacology
  • Europe
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology
  • Fruit / chemistry*
  • Fruit / metabolism
  • Hydroxybenzoates / chemistry
  • Hydroxybenzoates / isolation & purification*
  • Hydroxybenzoates / pharmacology
  • Hypoglycemic Agents / chemistry
  • Hypoglycemic Agents / isolation & purification
  • Hypoglycemic Agents / pharmacology
  • Iridoids / chemistry
  • Iridoids / isolation & purification*
  • Iridoids / pharmacology
  • Lonicera / chemistry*
  • Lonicera / metabolism
  • Neuroprotective Agents / chemistry
  • Neuroprotective Agents / isolation & purification
  • Neuroprotective Agents / pharmacology
  • Phytochemicals / chemistry
  • Phytochemicals / isolation & purification
  • Phytochemicals / pharmacology
  • Plant Extracts / chemistry
  • Sunscreening Agents / chemistry
  • Sunscreening Agents / isolation & purification
  • Sunscreening Agents / pharmacology

Substances

  • Anthocyanins
  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Antioxidants
  • Cardiotonic Agents
  • Coumaric Acids
  • Flavonoids
  • Hydroxybenzoates
  • Hypoglycemic Agents
  • Iridoids
  • Neuroprotective Agents
  • Phytochemicals
  • Plant Extracts
  • Sunscreening Agents