Altered gut microbiota by azithromycin attenuates airway inflammation in allergic asthma

J Allergy Clin Immunol. 2020 May;145(5):1466-1469.e8. doi: 10.1016/j.jaci.2020.01.044. Epub 2020 Feb 7.

Authors

Han-Ki Park¹, Youngwoo Choi², Dong-Hyun Lee², Sujeong Kim¹, Jong-Myung Lee¹, Sae Won Choi³, Hee-Ra Lee⁴, Mina Rho⁵, Hae-Sim Park⁶

Affiliations

¹ Department of Allergy and Clinical Immunology, School of Medicine, Kyungpook National University, Daegu, Korea.
² Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
³ Office of Hospital Information, Seoul National University Hospital, Seoul, Korea.
⁴ MD Healthcare Inc, Seoul, Korea.
⁵ Department of Computer Science and Engineering, Hanyang University, Seoul, Korea.
⁶ Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea. Electronic address: hspark@ajou.ac.kr.

PMID: 32035985
DOI: 10.1016/j.jaci.2020.01.044

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Allergens / immunology
Animals
Anti-Bacterial Agents / pharmacology*
Asthma / immunology
Asthma / microbiology*
Asthma / therapy
Azithromycin / pharmacology*
Bronchoalveolar Lavage Fluid / cytology
Bronchoalveolar Lavage Fluid / immunology
Bronchoalveolar Lavage Fluid / microbiology
Cefixime / pharmacology*
Cytokines / immunology
Fecal Microbiota Transplantation
Feces / microbiology
Female
Gastrointestinal Microbiome / drug effects*
Mice, Inbred BALB C
Ovalbumin / immunology
Th2 Cells / drug effects
Th2 Cells / immunology

Substances

Allergens
Anti-Bacterial Agents
Cytokines
Azithromycin
Ovalbumin
Cefixime