Benign tumoral melanosis of a cervical lymph node in a child

Int J Pediatr Otorhinolaryngol. 2020 May:132:109916. doi: 10.1016/j.ijporl.2020.109916. Epub 2020 Jan 30.

Abstract

We present a pediatric case of benign tumoral melanosis in a cervical lymph node arising from congenital pigmented lesions of the anterior neck. This is the first reported pediatric case not associated with regressed melanoma or trauma. Tumoral melanosis is a rare phenomenon which describes a pigmented lesion like melanoma; however, histology demonstrates melanin-laden macrophages without malignant cells. In the few reported cases, tumoral melanosis has arisen in the skin or lymph node and associated with a regressed melanoma, pigmented basal cell carcinoma or mycosis fungoides. We discuss the pathology of this disease process, and the work up in a pediatric patient.

Keywords: Cervical lymph node; Congenital nevus; Pediatric neck mass; Tumoral melanosis.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology*
  • Melanosis / diagnostic imaging
  • Melanosis / pathology*
  • Neck / diagnostic imaging
  • Skin / pathology
  • Tomography, X-Ray Computed