A Review of Biologically Active Natural Products from Mediterranean Wild Edible Plants: Benefits in the Treatment of Obesity and Its Related Disorders

Molecules. 2020 Feb 3;25(3):649. doi: 10.3390/molecules25030649.

Abstract

Wild foods constitute an essential component of people's diets around the world. According to the Food and Agriculture Organization (FAO), over 100 million people in the EU consume wild foods, while 65 million collect some form of wild food themselves. The Mediterranean basin is a biodiversity hotspot of wild edible species. Nowadays, due to the renewed interest in alimurgic plants and the recent findings on the beneficial role of their phytochemical constituents, these species have been defined as "new functional foods". Research on natural products has recently regained importance with the growing understanding of their biological significance. Botanical food supplements marketed for weight and fat loss in obese subjects will be one of the most important items in marketed nutraceuticals. The aim of this report was to review the phytochemical compounds of Mediterranean wild edible species and their therapeutic potential against obesity and its related disorders. Results on the in vitro and in vivo activity of the most interesting plant extracts and their bioactive components are presented and discussed. The most interesting discoveries on their mechanisms of action are reported as well. Overall, this contribution highlights the importance and beneficial health roles of wild edible species.

Keywords: alimurgic plant; biodiversity; obesity; phytochemical compound; wild.

Publication types

  • Review

MeSH terms

  • Adipogenesis
  • Biodiversity
  • Biological Products / chemistry
  • Biological Products / pharmacology*
  • Biological Products / therapeutic use
  • Carbohydrate Metabolism / drug effects
  • Dietary Supplements*
  • Humans
  • Lipase / antagonists & inhibitors
  • Lipase / metabolism
  • Mediterranean Region
  • Molecular Structure
  • Obesity / drug therapy
  • Obesity / etiology
  • Obesity / metabolism
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacology
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plants, Edible / chemistry*

Substances

  • Biological Products
  • Phytochemicals
  • Plant Extracts
  • Lipase
  • PNLIP protein, human