Troubleshooting Complex Vascular Cases in the Kidney Transplant Recipient: Vascular Anomalies, Challenging Vessel Diseases, and Procedural Disasters

Curr Urol Rep. 2020 Feb 4;21(1):7. doi: 10.1007/s11934-020-0958-5.

Abstract

Purpose of review: To update the most relevant literature regarding complex cases during kidney transplant setting that recipient presents by himself, especially during implantation surgery due to vascular diseases and/or urinary tract anomalies.

Recent findings: Increasing age of donors and recipients is leading to an increased complexity of kidney transplant implantation surgery. In addition, the high peripheral vascular disease prevalence worldwide increases difficulty of surgery and decreases long-term outcomes as well. Moreover, it also increases transplant morbidity and mortality, both overall and cardiovascular, and finally clearly decreases graft survival. However, dialysis alternative has even worse outcomes in terms of mortality, with a proportional risk of death 2.66 higher compared with transplanted patients. Aorto-iliac prosthesis and 3rd and 4th transplants in occupied iliac fossae do also represent a challenging situation with a clearly increased morbidity and mortality. In some of those particular conditions, orthotopic kidney transplant technique is an alternative with good functional and survival outcomes, but not exempt of complications. Kidney transplant in vascular complex recipients has worse outcomes compared with conventional non-risky population. It remains a challenging surgical and medical procedure with higher morbidity and mortality, and decreased graft survival. However, dialysis mortality is still even greater and a transplant attempt might be justified. Orthotopic kidney transplant technique might play a role in selected patients with aorto-iliac unworkable segments or even in patients with special urinary tract conditions.

Keywords: Complex vascular transplant; Kidney transplant; Orthotopic kidney transplant; Peripheral vascular disease; Urinary diversions; Vascular anomalies.

Publication types

  • Review

MeSH terms

  • Anastomosis, Surgical / adverse effects
  • Humans
  • Iatrogenic Disease
  • Intraoperative Complications / therapy
  • Kidney / blood supply
  • Kidney / surgery
  • Kidney Failure, Chronic / complications
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / methods*
  • Peripheral Vascular Diseases / complications
  • Peripheral Vascular Diseases / surgery
  • Reoperation
  • Transplants / blood supply
  • Transplants / surgery
  • Treatment Outcome
  • Urogenital Abnormalities / surgery*
  • Vascular Diseases / complications
  • Vascular Diseases / surgery*
  • Vascular Malformations / complications
  • Vascular Malformations / surgery*
  • Vascular System Injuries / surgery*