Kidney transplantation on extracorporeal life support for primary cardiac allograft dysfunction

J Card Surg. 2020 Mar;35(3):725-728. doi: 10.1111/jocs.14451. Epub 2020 Feb 4.

Abstract

Patients undergoing heart-kidney transplants who have primary graft dysfunction (PGD) of the heart are at risk of losing both organs, which may cause reluctance on the part of the transplant team to proceed with transplanting the kidney while the transplanted heart is being supported by mechanical device. We describe a case series in which 2 patients received kidney transplants while on veno-arterial ECMO support for PGD after heart transplant. Both patients are alive more than 1 year following transplant, with good cardiac and renal function and no signs of cardiac rejection. Kidney transplant surgery is safe for patients on veno-arterial ECMO support for cardiac PGD. It allows the heart recipient to receive a kidney from the same donor with both immunologic and survival advantages.

Keywords: extracorporeal membrane oxygenation; heart-kidney transplant; kidney transplant; primary graft dysfunction.

Publication types

  • Case Reports

MeSH terms

  • Allografts
  • Extracorporeal Membrane Oxygenation*
  • Heart Transplantation / methods*
  • Humans
  • Kidney Transplantation / methods*
  • Male
  • Middle Aged
  • Primary Graft Dysfunction / therapy*
  • Treatment Outcome