Milestones in the fight to eliminate trachoma

Ophthalmic Physiol Opt. 2020 Mar;40(2):66-74. doi: 10.1111/opo.12666. Epub 2020 Feb 3.

Abstract

Purpose: Trachoma, a chronic conjunctivitis that can result in vision loss from trichiasis, is targeted for global elimination by 2020. Several milestones in the long process towards elimination are noteworthy for the impact they have had on changing or accelerating progress. The purpose of this review is to describe the milestones and the impact they have had both for trachoma elimination and beyond.

Findings: Eight milestones are presented. They are discovery of the causative agent; development of a clinical grading scheme; establishment of the World Health Organization Alliance for the Global Elimination of Trachoma by 2020; setting targets that define elimination; building an evidence base for trichiasis surgery; azithromycin donation programme; use of the SAFE strategy (Surgery, Antibiotics, Facial cleanliness, and Environmental improvement); and The Global Trachoma Mapping Project.

Summary: These milestones have significantly pushed the progress towards elimination. Despite challenges to achieving the goal of elimination by 2020, there is continued commitment into the future to ensure that this preventable cause of blindness is no longer a threat.

Keywords: Chlamydia trachomatis; azithromycin; facial cleanliness; global mapping; trachoma.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Blindness / epidemiology
  • Blindness / etiology*
  • Blindness / prevention & control
  • Eye Infections, Bacterial / complications
  • Eye Infections, Bacterial / drug therapy*
  • Global Health
  • Humans
  • Prevalence
  • Trachoma / complications
  • Trachoma / drug therapy*
  • World Health Organization

Substances

  • Anti-Bacterial Agents