Carbon monoxide poisoning

Hiroshi Kinoshita; Hülya Türkan; Slavica Vucinic; Shahab Naqvi; Rafik Bedair; Ramin Rezaee; Aristides Tsatsakis

doi:10.1016/j.toxrep.2020.01.005

Carbon monoxide poisoning

Toxicol Rep. 2020 Jan 20:7:169-173. doi: 10.1016/j.toxrep.2020.01.005. eCollection 2020.

Authors

Hiroshi Kinoshita¹, Hülya Türkan², Slavica Vucinic³, Shahab Naqvi⁴, Rafik Bedair⁵, Ramin Rezaee^{6

7}, Aristides Tsatsakis⁸

Affiliations

¹ Department of Forensic Medicine, Faculty of Medicine, Kagawa University, Kagawa, 761-0793, Japan.
² Ministry of national Defense, General Directorate of Health Services, Ankara, Turkey.
³ National Poison Control Centre, Military Medical Academy, Medical Faculty, University of Defense, Belgrade, Serbia.
⁴ Anaesthesiology and Intensive Care, Rawal Institute of Health Sciences, Islamabad, Pakistan.
⁵ Adult Critical Care Directorate, St. George's University Hospitals, Blackshaw Road, London, SW17 9WL, United Kingdom.
⁶ Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
⁷ Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
⁸ Department of Toxicology & Forensic Sciences, Medical School, University of Crete, Voutes Campus, Heraklion, 71003, Greece.

Abstract

Carbon monoxide (CO) is the leading cause of poisoning deaths in many countries, including Japan. Annually, CO poisoning claims about 2000-5000 lives in Japan, which is over half of the total number of poisoning deaths. This paper discusses the physicochemical properties of CO and the toxicological evaluation of CO poisoning.

Keywords: Carbon monoxide; Carboxyhemoglobin; Measurement; Pathophysiology; Toxicity.

Publication types

Review