Pharmacologically induced thyreopathy in patients with cardiovascular disease

Vnitr Lek. 2020 Winter;65(12):802-808.

Abstract

Thyroid gland function is mediated by thyreoideal hormones, in which iodine is very important structural part. High iodine intake, can initiate thyroid dysfunction. Amiodarone induced hypothyroidism is treated with levothyroxine and amiodarone taking is not interrupted. Amiodarone induced hyperthyroidism is divided into two subtypes, which differ by mechanism of origin and treatment strategy. In patients with cardiovascular disease is higher possibility of getting substances, with high content of iodine in diagnostic-therapeutic examination with contrast or treatment with amiodarone. In this group of patients is necessary to control thyroid function regularly and to hold preventive actions.

Keywords: amiodarone; hyperthyroidism; hypothyroidism; iodine; thyroid dysfunction.

MeSH terms

  • Amiodarone / adverse effects
  • Anti-Arrhythmia Agents / adverse effects
  • Cardiovascular Diseases* / complications
  • Humans
  • Hyperthyroidism* / complications
  • Hypothyroidism* / etiology
  • Iodine
  • Thyroxine

Substances

  • Anti-Arrhythmia Agents
  • Iodine
  • Amiodarone
  • Thyroxine