vWFpp/ADAMTS13 ratio is a useful marker of postliver transplantation thrombotic microangiopathy: A pediatric case report

Lisa Duquenne; Samuel Balbeur; Emilie Everard; Raymond Reding; Stéphane Eeckhoudt; Bénédicte Brichard; Nathalie Godefroid; Emilien Derycke; Mina Komuta; Isabelle Scheers; Françoise Smets; Etienne Sokal; Xavier Stéphenne

doi:10.1002/ccr3.2495

vWFpp/ADAMTS13 ratio is a useful marker of postliver transplantation thrombotic microangiopathy: A pediatric case report

Clin Case Rep. 2019 Dec 10;8(1):41-46. doi: 10.1002/ccr3.2495. eCollection 2020 Jan.

Affiliations

¹ Division of Paediatric Gastroenterology and Hepatology Department of Paediatrics Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.
² Division of Paediatric Surgery Department of Surgery Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.
³ Laboratory of Haematology Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.
⁴ Division of Paediatric Haematology Department of Paediatrics Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.
⁵ Division of Paediatric Nephrology Department of Paediatrics Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.
⁶ Division of Emergency and Intensive Care Department of Paediatrics Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.
⁷ Department of Anatomopathology Cliniques Universitaires Saint Luc Université Catholique de Louvain Brussels Belgium.

Abstract

vWFpp/ADAMTS13 ratio should be further studied as a useful marker for diagnosis of thrombotic microangiopathy postliver transplantation. Immunosuppressive regimen modification and plasma supplementation can lead to recovery.

Keywords: pediatric liver transplantation; sirolimus; tacrolimus; thrombotic microangiopathy; vWFpp/ADAMTS13 ratio.

Publication types

Case Reports