Lipoic Acid Decorated Gold Nanoparticles and Their Application in the Detection of Lead Ions

J Nanomed Nanotechnol. 2019;10(6):10.35248/2157-7439.19.10.539. doi: 10.35248/2157-7439.19.10.539. Epub 2019 Dec 12.

Abstract

A simple colorimetric method has been developed for the detection of lead (Pb2+) in water samples using lipoic acid-functionalized gold nanoparticles. The lipoic acid-functionalized gold nanoparticles are induced to aggregate in the presence of the Pb2+ which results in a change in the color of the functionalized gold nanoparticles. The change in color and the amount of Pb2+ producing the change could be monitored via UV-visible spectrophotometry. A good correlation coefficient of 0.9927 was obtained for the calibration curve of the colorimetric method. The method was applied in the determination of Pb2+ in water samples and the results compared to that of measurement carried out with Atomic Absorption Spectroscopy.

Keywords: Absorption; Colorimetric; Gold nanoparticles; Lead; Lipoic acid; Sensor.