A two-herb formula inhibits osteoclastogenesis and suppresses NF-kB and MAPK pathways

J Ethnopharmacol. 2020 Apr 24:252:112625. doi: 10.1016/j.jep.2020.112625. Epub 2020 Jan 25.
No abstract available

Keywords: Lonicera japonica; NF-κB and MAPK pathways; Osteoclastogenesis; Rheumatoid arthritis; Rosa multiflora.

MeSH terms

  • Animals
  • Cell Culture Techniques
  • MAP Kinase Signaling System / drug effects*
  • Macrophages
  • NF-kappa B / metabolism*
  • Osteoclasts / pathology
  • Osteogenesis / drug effects*
  • Plant Extracts / pharmacology*
  • Rats

Substances

  • NF-kappa B
  • Plant Extracts