From the Data on Many, Precision Medicine for "One": The Case for Widespread Genomic Data Sharing

Serena Scollen; Angela Page; Julia Wilson

doi:10.1159/000481682

From the Data on Many, Precision Medicine for "One": The Case for Widespread Genomic Data Sharing

Biomed Hub. 2017 Nov 21;2(Suppl 1):104-110. doi: 10.1159/000481682. eCollection 2017 Nov-Dec.

Authors

Serena Scollen^{1

2}, Angela Page^{3

2}, Julia Wilson^{4

2}

Affiliations

¹ ELIXIR Hub, Cambridge, UK.
² Global Alliance for Genomics and Health, Toronto, ON, Canada.
³ Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁴ Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, UK.

Abstract

Within the decade, genome sequencing promises to become a routine part of healthcare around the globe. Many millions of genomes linked to health records will soon be available for researchers and clinicians to make use of to advance precision medicine. To realise the full impact of genomic medicine, genomic and clinical data must be interoperable across traditional geographic, jurisdictional, sectoral, and domain boundaries. Extremely large and diverse data sets are needed to provide a context for interpretation of genetic sequences. No single country or institution can achieve the necessary scale and diversity alone. Data must be shared within an internationally federated, learning health system.

Keywords: Big data; Cancer; ELIXIR; FAIR; Genome sequencing; Genomic medicine; Global Alliance for Genomics and Health; Precision medicine; Rare disease.

Publication types

Review