Permethrin, a synthetic pyrethroid categorized as a synthetic neurotoxic pyrethroid, is approved for treating scabies and pediculosis capitis. This medication operates within the arthropod nervous system, specifically targeting eggs, lice, and mites. Permethrin exerts its therapeutic effect by disrupting sodium transport across neuronal membranes in arthropods, inducing depolarization. This mechanism ultimately leads to respiratory paralysis in the affected arthropod, establishing permethrin as a potent agent in managing scabies and pediculosis. This activity will comprehensively cover permethrin's indications, mode of action, and contraindications, equipping healthcare team members with essential knowledge to treat patients with scabies and pediculosis effectively.
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