Chemical investigation of the lichen Parmotrema dilatatum led to the isolation of a new chlorinated compound, named dilatatone (1), along with a known compound, sernanderin (2). Their chemical structures were determined by analysis of their 1 D and 2 D NMR spectra, HRESIMS, and ECD data. Both compounds showed weak α-glucosidase inhibitor activity.
Keywords: Parmotrema dilatatum; dilatatone; lichen; α-glucosidase inhibitory activity.